Don Best NFL Picks for Week 1

If you’re looking for the best NFL picks for Week 1, look no further than Don Best! Our team of experts has analyzed all the matchups and provides winning picks for every game.

New England Patriots (-6) vs. Pittsburgh Steelers

The New England Patriots (-6) will take on the Pittsburgh Steelers in Week 1 of the NFL season. The Patriots are coming off a Super Bowl loss to the Eagles, while the Steelers are coming off a disappointing end to their season, losing to the Jaguars in the divisional round.

The Patriots are favored by 6 points in this matchup, and for good reason. They are simply the better team, and they have home-field advantage. Tom Brady is the best quarterback in the league, and he will be able to pick apart the Steelers secondary. The Patriots also have a great running game, led by Dion Lewis, which will help them control the clock and keep the Steelers offense off the field.

The Steelers do have some weapons of their own, however. Antonio Brown is one of the best wide receivers in the league, and Le’Veon Bell is one of the best running backs. They also have a good quarterback in Ben Roethlisberger. But ultimately, I think the Patriots will be too much for them, and they will win by at least a touchdown.

Green Bay Packers (-3) vs. Minnesota Vikings

The Green Bay Packers are 3-point favorites against the Minnesota Vikings in Week 1 of the NFL season. The Packers have one of the best quarterbacks in the league in Aaron Rodgers, and they also have a strong defense. The Vikings have a good defense, but their offense may struggle this season.

Baltimore Ravens (-7) vs. Cleveland Browns

The Baltimore Ravens are one of the best teams in the NFL, and they are playing at home against a Cleveland Browns team that is in rebuilding mode. The Ravens should win this game easily, and they are 7-point favorites.

Kansas City Chiefs (-10) vs. Jacksonville Jaguars

The Kansas City Chiefs are 10-point favorites over the Jacksonville Jaguars in Week 1 of the NFL season. The Chiefs are coming off a Super Bowl win, while the Jaguars went 0-16 last season.

The Chiefs are one of the best teams in the league and should win this game easily. However, the Jaguars have a good defense and could keep it close. If you are looking for an upset pick, Jacksonville could be worth a look.

Los Angeles Rams (-3) vs. Carolina Panthers

The Rams are coming off a disappointing loss in the Super Bowl, but they’re still one of the best teams in the NFL. They’ll be motivated to get off to a fast start this season, and they have the talent to do it. The Panthers are a good team, but they’re not on the same level as the Rams. I like Los Angeles to win this game by at least a field goal.

Tampa Bay Buccaneers (-3) vs. New Orleans Saints

The Tampa Bay Buccaneers are set to take on the New Orleans Saints in Week 1 of the NFL season. The Buccaneers are 3-point favorites in this matchup.

This will be the first time these two teams have met since last season, when the Buccaneers defeated the Saints, 31-24. In that game, Tampa Bay quarterback Jameis Winston threw for 207 yards and two touchdowns, while also rushing for a score.

The Saints will be looking to exact some revenge in this matchup, but they will have their work cut out for them against a talented Buccaneers team. Tampa Bay has one of the best defenses in the league, and they should be able to contain Saints quarterback Drew Brees.

On offense, the Buccaneers will look to take advantage of a Saints defense that was gashed by the run last season. Running backDoug Martin is coming off a down year, but he should be motivated to bounce back in 2017. Look for him to have a big game against the Saints.

Prediction: Tampa Bay 27, New Orleans 24

Cincinnati Bengals (-3) vs. Seattle Seahawks

The Seahawks and Bengals meet in the first game of Week 1, on Sunday at 4:05 p.m. ET. Seattle is coming off a disappointing 9-7 season in which it missed the playoffs, while Cincinnati struggled to a 6-9-1 record.

Cincinnati has lost four straight games to Seattle dating back to 2011, but the Seahawks will be without star quarterback Russell Wilson for this matchup. Seattle’s offense will also be without receiver Doug Baldwin, who is nursing a knee injury.

With Wilson and Baldwin out, the Seahawks are expected to struggle offensively. The Bengals, meanwhile, have a strong defense that should be able to contain Seattle’s offense. Cincinnati also has a good running game with running back Joe Mixon, who ran for 1,168 yards and eight touchdowns last season.

The Bengals are 3-point favorites over the Seahawks in this game. Cincinnati should be able to win this game by at least a touchdown.

San Francisco 49ers (-6) vs. Arizona Cardinals

The San Francisco 49ers are 6-point favorites over the Arizona Cardinals in Week 1 of the NFL season. The 49ers are coming off a Super Bowl appearance, and the Cardinals are coming off a disappointing season. The 49ers have one of the best defenses in the NFL, and the Cardinals have one of the worst. The 49ers should win this game easily.

New York Jets (-1) vs. Buffalo Bills

The Bills shocked many people last year by making the playoffs, but I don’t think they’re going to be able to replicate that success this season. The Jets, on the other hand, are a team on the rise. I like Sam Darnold to take another step forward in his development and lead New York to a Week 1 victory.

Dallas Cowboys (-3) vs. Los Angeles Chargers

The Dallas Cowboys take on the Los Angeles Chargers in Week 1 of the NFL season. The Cowboys are favored by three points in this matchup.

The Dallas Cowboys are coming off a disappointing season in which they finished with a 9-7 record. The Cowboys offense was hampered by injuries last season, but they should be healthy heading into this season. The Cowboys will be led by quarterback Dak Prescott and running back Ezekiel Elliott. The Chargers are coming off a disappointing season as well, finishing with a 8-8 record. The Chargers offense was also hampered by injuries last season, but they too should be healthy heading into this new season. The Chargers will be led by quarterback Philip Rivers and wide receiver Keenan Allen.

This should be a close matchup between two evenly matched teams. The Cowboys are slight favorites, but the Chargers could easily pull off the upset.